Organ |
liver |
Age classes |
adolescent |
Gender |
M |
Condition |
8 weeks |
phase I metabolism > aldehyde dehydrogenase > 3-phenyl propionaldehyde > microsomes |
6.1 nmol/min/mg protein (sd=1.3)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase I metabolism > aldehyde dehydrogenase > 2-ethylhexanal > microsomes |
5.4 nmol/min/mg protein (sd=1.9)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase I metabolism > alcohol dehydrogenase > 2-ethylhexanol > cytosol |
32.7 nmol/min/mg protein (sd=4.4)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT1A6 > 1-naphthol glucuronidation > microsomes |
5.91 nmol/min/mg protein (sd=1.41)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT > mono(2-ethylhexyl)phthalate glucuronidation > microsomes |
0.66 nmol/min/mg protein (sd=0.1)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT > bis-phenol A glucuronidation > microsomes |
21.63 nmol/min/mg protein (sd=2.1)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
enzyme activity > lipase > microsomes |
4964 pmol/min/mg protein (sd=1040)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
enzyme activity > lipase > homogenates |
1339 pmol/mg protein (sd=261)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|