Organ |
liver |
Age classes |
adolescent |
Gender |
M |
phase I metabolism > CYP3A4 > testosterone 6β-hydroxylation > microsomes |
1140 pmol/min/mg protein (sd=42)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|
phase I metabolism > CYP3A4 > nifedipine oxidation > microsomes |
1414 pmol/min/mg protein (sd=122)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|
phase I metabolism > CYP2E1 > chlorzoxazone 6-hydroxylation > microsomes |
278 pmol/min/mg protein (sd=45)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|
phase I metabolism > CYP2D6 > dextromethorphan O-demethylation > microsomes |
2387 pmol/min/mg protein (sd=264)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|
phase I metabolism > CYP2A6 > coumarin 7-hydroxylation > microsomes |
30.8 pmol/min/mg protein (sd=8.4)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|
phase I metabolism > CYP1A2 > phenacetin O-deethylation > microsomes |
312 pmol/min/mg protein (sd=49)
|
Li et al., 2006 - Li, J., Liu, Y., Zhang, J.W., Wei, H. and Yang, L. (2006) Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs. Comp Med 56, 286-90.
|