Organ |
liver |
Age classes |
adolescent |
Gender |
M |
Condition |
8 weeks |
phase I metabolism > aldehyde dehydrogenase > 3-phenyl propionaldehyde > microsomes |
21 nmol/min/mg protein (sd=5.2)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase I metabolism > aldehyde dehydrogenase > 2-ethylhexanal > microsomes |
32.8 nmol/min/mg protein (sd=10.8)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase I metabolism > alcohol dehydrogenase > 2-ethylhexanol > cytosol |
26.3 nmol/min/mg protein (sd=6.2)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT1A6 > 1-naphthol glucuronidation > microsomes |
8.53 nmol/min/mg protein (sd=1.23)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT > mono(2-ethylhexyl)phthalate glucuronidation > microsomes |
0.51 nmol/min/mg protein (sd=0.12)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
phase II metabolism > UGT > bis-phenol A glucuronidation > microsomes |
10.8 nmol/min/mg protein (sd=2.82)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
enzyme activity > lipase > microsomes |
2129 pmol/min/mg protein (sd=333)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|
enzyme activity > lipase > homogenates |
718 pmol/mg protein (sd=152)
|
Ito et al., 2005 - Ito, Y., Yokota, H., Wang, R., Yamanoshita, O., Ichihara, G., Wang, H., Kurata, Y., Takagi, K. and Nakajima, T. (2005) Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets. Arch Toxicol 79, 147-54.
|