Organ |
liver |
Age classes |
adolescent |
Gender |
M |
Remark |
200-250 g |
phase I metabolism > CYP3A4 > ethylmorphine N-demethylation > microsomes |
12.65 nmol/min/mg protein (sd=13.38)
|
Menegez et al., 1999 - Meneguz, A., Fortuna, S., Lorenzini, P. and Volpe, M.T. (1999) Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo. Exp Toxicol Pathol 51, 392-6.
|
phase I metabolism > CYP2E1 > aniline 4-hydroxylation > microsomes |
0.58 nmol/min/mg protein (sd=0.74)
|
Menegez et al., 1999 - Meneguz, A., Fortuna, S., Lorenzini, P. and Volpe, M.T. (1999) Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo. Exp Toxicol Pathol 51, 392-6.
|
phase I metabolism > CYP2B > pentoxyresorufin O-deethylation > microsomes |
1.4 nmol/min/mg protein (sd=2.2)
|
Menegez et al., 1999 - Meneguz, A., Fortuna, S., Lorenzini, P. and Volpe, M.T. (1999) Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo. Exp Toxicol Pathol 51, 392-6.
|
phase I metabolism > CYP1A1 > ethoxyresorufin O-deethylation > microsomes |
7.4 nmol/min/mg protein (sd=12.9)
|
Menegez et al., 1999 - Meneguz, A., Fortuna, S., Lorenzini, P. and Volpe, M.T. (1999) Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo. Exp Toxicol Pathol 51, 392-6.
|